Recombinant Human p-Tau217 Protein
Key features and details
- Product Name:Recombinant Human p-Tau217 Protein
- Expression Systems:Escherichia coli
- Species:Human
- Formulation:Phosphate buffered saline
-
Brand:
CAT.NO. : AXP6612
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Size:
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Product Details
Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Overview
|
Protein name |
Microtubule-associated protein tau |
|
Gene name |
MAPT |
|
Accession |
P10636-8 |
|
Organism |
Homo sapiens (Human) |
|
Product name |
Recombinant Human p-Tau217 Protein |
|
Predicted molecular mass |
48 kDa |
|
Expression host |
Escherichia coli |
|
Modification |
Phosphorylation |
|
Purification tag |
6xHis at C-terminus |
|
Usage |
This product is validated for use as an immunogen and as a reagent in immunological assays |
|
Form |
Liquid |
|
Buffer |
Phosphate buffered saline |
Storage
Shipped on dry ice.
Avoid repeated freeze-thaw cycles. Upon receipt,
* 2 days when stored at 2 to 8 °C
* 3 months when aliquoted and stored at -20 °C or below
Avoid repeated freeze-thaw cycles. Upon receipt,
* 2 days when stored at 2 to 8 °C
* 3 months when aliquoted and stored at -20 °C or below
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